Tonantzitlolone cytotoxicity toward renal cancer cells is PKCθ- and HSF1-dependent

Elucidating the targets and mechanism of action of natural products is strategically important prior to drug development and assessment of potential clinical applications. In this report, we elucidated the main targets and mechanism of action of the natural product tonantzitlolone (TZL) in clear cel...

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發表在:Oncotarget
Main Authors: Sourbier, Carole, Scroggins, Bradley T., Mannes, Philip Z., Liao, Pei-Jyun, Siems, Karsten, Wolf, Dietmar, Beutler, John A., Linehan, W. Marston, Neckers, Leonard
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2015
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745775/
https://ncbi.nlm.nih.gov/pubmed/26298773
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