Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model

Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer. However, especially after incomplete cytoreduction, disease progression is common and this is likely due to limited ti...

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Pubblicato in:Oncotarget
Autori principali: Gremonprez, Félix, Descamps, Benedicte, Izmer, Andrei, Vanhove, Christian, Vanhaecke, Frank, De Wever, Olivier, Ceelen, Wim
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745770/
https://ncbi.nlm.nih.gov/pubmed/26375674
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