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Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer

Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics. Paclitaxel-loaded genipin-crosslinked gelatin microsp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: De Clercq, Kaat, Xie, Feifan, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Ceelen, Wim, Vervaet, Chris
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795903/
https://ncbi.nlm.nih.gov/pubmed/31619730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51419-y
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