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Preclinical evaluation of local prolonged release of paclitaxel from gelatin microspheres for the prevention of recurrence of peritoneal carcinomatosis in advanced ovarian cancer

Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics. Paclitaxel-loaded genipin-crosslinked gelatin microsp...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: De Clercq, Kaat, Xie, Feifan, De Wever, Olivier, Descamps, Benedicte, Hoorens, Anne, Vermeulen, An, Ceelen, Wim, Vervaet, Chris
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6795903/
https://ncbi.nlm.nih.gov/pubmed/31619730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51419-y
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