Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model

Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer. However, especially after incomplete cytoreduction, disease progression is common and this is likely due to limited ti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gremonprez, Félix, Descamps, Benedicte, Izmer, Andrei, Vanhove, Christian, Vanhaecke, Frank, De Wever, Olivier, Ceelen, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745770/
https://ncbi.nlm.nih.gov/pubmed/26375674
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