Pretreatment with VEGF(R)-inhibitors reduces interstitial fluid pressure, increases intraperitoneal chemotherapy drug penetration, and impedes tumor growth in a mouse colorectal carcinomatosis model

Cytoreductive surgery combined with intraperitoneal chemotherapy (IPC) is currently the standard treatment for selected patients with peritoneal carcinomatosis of colorectal cancer. However, especially after incomplete cytoreduction, disease progression is common and this is likely due to limited ti...

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Publicat a:Oncotarget
Autors principals: Gremonprez, Félix, Descamps, Benedicte, Izmer, Andrei, Vanhove, Christian, Vanhaecke, Frank, De Wever, Olivier, Ceelen, Wim
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745770/
https://ncbi.nlm.nih.gov/pubmed/26375674
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