Inhibition of autophagy potentiates pemetrexed and simvastatin-induced apoptotic cell death in malignant mesothelioma and non-small cell lung cancer cells

Pemetrexed, a multitarget antifolate used to treat malignant mesothelioma and non-small cell lung cancer (NSCLC), has been shown to stimulate autophagy. In this study, we determined whether autophagy could be induced by pemetrexed and simvastatin cotreatment in malignant mesothelioma and NSCLC cells...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Hwang, Ki-Eun, Kim, Young-Suk, Jung, Jae-Wan, Kwon, Su-Jin, Park, Do-Sim, Cha, Byong-Ki, Oh, Seon-Hee, Yoon, Kwon-Ha, Jeong, Eun-Taik, Kim, Hak-Ryul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745741/
https://ncbi.nlm.nih.gov/pubmed/26334320
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