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At the centre of neuronal, synaptic and axonal pathology in murine prion disease: degeneration of neuroanatomically linked thalamic and brainstem nuclei

AIMS: The processes by which neurons degenerate in chronic neurodegenerative diseases remain unclear. Synaptic loss and axonal pathology frequently precede neuronal loss and protein aggregation demonstrably spreads along neuroanatomical pathways in many neurodegenerative diseases. The spread of neur...

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Detalhes bibliográficos
Publicado no:Neuropathol Appl Neurobiol
Main Authors: Reis, Renata, Hennessy, Edel, Murray, Caoimhe, Griffin, Éadaoin W., Cunningham, Colm
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744702/
https://ncbi.nlm.nih.gov/pubmed/25727649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nan.12232
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