Huntington's Disease (HD): Degeneration of Select Nuclei, Widespread Occurrence of Neuronal Nuclear and Axonal Inclusions in the Brainstem

Huntington's disease (HD) is a progressive polyglutamine disease that leads to a severe striatal and layer‐specific neuronal loss in the cerebral neo‐and allocortex. As some of the clinical symptoms (eg, oculomotor dysfunctions) suggested a degeneration of select brainstem nuclei, we performed...

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Detalhes bibliográficos
Main Authors: Rüb, Udo, Hentschel, Matthias, Stratmann, Katharina, Brunt, Ewout, Heinsen, Helmut, Seidel, Kay, Bouzrou, Mohamed, Auburger, Georg, Paulson, Henry, Vonsattel, Jean‐Paul, Lange, Herwig, Korf, Horst‐Werner, den Dunnen, Wilfred
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160739/
https://ncbi.nlm.nih.gov/pubmed/24779419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12115
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