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Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier
Microglia are integral functional elements of the central nervous system, but the contribution of these cells to the structural integrity of the neurovascular unit has not hitherto been assessed. We show here that following blood–brain barrier (BBB) breakdown, P2RY12 (purinergic receptor P2Y, G-prot...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743790/ https://ncbi.nlm.nih.gov/pubmed/26755608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520398113 |
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