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Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier

Microglia are integral functional elements of the central nervous system, but the contribution of these cells to the structural integrity of the neurovascular unit has not hitherto been assessed. We show here that following blood–brain barrier (BBB) breakdown, P2RY12 (purinergic receptor P2Y, G-prot...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Lou, Nanhong, Takano, Takahiro, Pei, Yong, Xavier, Anna L., Goldman, Steven A., Nedergaard, Maiken
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743790/
https://ncbi.nlm.nih.gov/pubmed/26755608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520398113
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