Combination therapy of tiotropium and ciclesonide attenuates airway inflammation and remodeling in a guinea pig model of chronic asthma

BACKGROUND: The long-acting anticholinergic tiotropium has recently been registered for the treatment of asthma, and its use is associated with a reduction in exacerbation frequency. Anti-inflammatory and anti-remodeling effects of tiotropium have been demonstrated in in vitro and in vivo models. Be...

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Bibliografische gegevens
Gepubliceerd in:Respir Res
Hoofdauteurs: Kistemaker, Loes E. M., Bos, I. Sophie T., Menzen, Mark H., Maarsingh, Harm, Meurs, Herman, Gosens, Reinoud
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743207/
https://ncbi.nlm.nih.gov/pubmed/26846267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0327-6
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