Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

Inositol pyrophosphates, such as diphospho-myo-inositol pentakisphosphates (InsP(7)), are an important family of signalling molecules, implicated in many cellular processes and therapeutic indications including insulin secretion, glucose homeostasis and weight gain. To understand their cellular func...

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Publicat a:Nat Commun
Autors principals: Pavlovic, Igor, Thakor, Divyeshsinh T., Vargas, Jessica R., McKinlay, Colin J., Hauke, Sebastian, Anstaett, Philipp, Camuña, Rafael C., Bigler, Laurent, Gasser, Gilles, Schultz, Carsten, Wender, Paul A., Jessen, Henning J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743007/
https://ncbi.nlm.nih.gov/pubmed/26842801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10622
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