Cellular delivery and photochemical release of a caged inositol-pyrophosphate induces PH-domain translocation in cellulo

Inositol pyrophosphates, such as diphospho-myo-inositol pentakisphosphates (InsP(7)), are an important family of signalling molecules, implicated in many cellular processes and therapeutic indications including insulin secretion, glucose homeostasis and weight gain. To understand their cellular func...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Pavlovic, Igor, Thakor, Divyeshsinh T., Vargas, Jessica R., McKinlay, Colin J., Hauke, Sebastian, Anstaett, Philipp, Camuña, Rafael C., Bigler, Laurent, Gasser, Gilles, Schultz, Carsten, Wender, Paul A., Jessen, Henning J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743007/
https://ncbi.nlm.nih.gov/pubmed/26842801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10622
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