miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1

Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to o...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Zhang, Yi, Zhou, Shu-yan, Yan, Hai-zhao, Xu, Dan-dan, Chen, Hai-xuan, Wang, Xiao-yan, Wang, Xiao, Liu, Yu-ting, Zhang, Li, Wang, Sheng, Zhou, Peng-jun, Fu, Wu-yu, Ruan, Bi-bo, Ma, Dong-lei, Wang, Ying, Liu, Qiu-ying, Ren, Zhe, Liu, Zhong, Zhang, Rong, Wang, Yi-fei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742816/
https://ncbi.nlm.nih.gov/pubmed/26847520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19995
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