miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1

Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to o...

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Publicado no:Sci Rep
Main Authors: Zhang, Yi, Zhou, Shu-yan, Yan, Hai-zhao, Xu, Dan-dan, Chen, Hai-xuan, Wang, Xiao-yan, Wang, Xiao, Liu, Yu-ting, Zhang, Li, Wang, Sheng, Zhou, Peng-jun, Fu, Wu-yu, Ruan, Bi-bo, Ma, Dong-lei, Wang, Ying, Liu, Qiu-ying, Ren, Zhe, Liu, Zhong, Zhang, Rong, Wang, Yi-fei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742816/
https://ncbi.nlm.nih.gov/pubmed/26847520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19995
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