Sp1 and c-Myc modulate drug resistance of leukemia stem cells by regulating survivin expression through the ERK-MSK MAPK signaling pathway

BACKGROUND: Acute myeloid leukemia (AML) is initiated and maintained by a subset of self-renewing leukemia stem cells (LSCs), which contribute to the progression, recurrence and therapeutic resistance of leukemia. However, the mechanisms underlying the maintenance of LSCs drug resistance have not be...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Cancer
Päätekijät: Zhang, Yi, Chen, Hai-xuan, Zhou, Shu-yan, Wang, Shao-xiang, Zheng, Kai, Xu, Dan-dan, Liu, Yu-ting, Wang, Xiao-yan, Wang, Xiao, Yan, Hai-zhao, Zhang, Li, Liu, Qiu-ying, Chen, Wan-qun, Wang, Yi-fei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2015
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357193/
https://ncbi.nlm.nih.gov/pubmed/25890196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0326-0
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia