miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1

Drug resistance is one of the leading causes of failed cancer therapy in the treatment of acute myeloid leukemia. Although the mechanisms of resistance are poorly understood, they may be related to the presence of leukemia stem cells (LSCs). Down-regulation of the miR-203 reportedly contributes to o...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Zhang, Yi, Zhou, Shu-yan, Yan, Hai-zhao, Xu, Dan-dan, Chen, Hai-xuan, Wang, Xiao-yan, Wang, Xiao, Liu, Yu-ting, Zhang, Li, Wang, Sheng, Zhou, Peng-jun, Fu, Wu-yu, Ruan, Bi-bo, Ma, Dong-lei, Wang, Ying, Liu, Qiu-ying, Ren, Zhe, Liu, Zhong, Zhang, Rong, Wang, Yi-fei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742816/
https://ncbi.nlm.nih.gov/pubmed/26847520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19995
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