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Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy

The biological function of interleukin-10 (IL-10), a pleiotropic cytokine with an essential role in inflammatory processes, is known to be affected by glycosaminoglycans (GAGs). GAGs are highly negatively charged polysaccharides and integral components of the extracellular matrix with important func...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Künze, Georg, Köhling, Sebastian, Vogel, Alexander, Rademann, Jörg, Huster, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742770/
https://ncbi.nlm.nih.gov/pubmed/26677224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681759
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