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Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy

The biological function of interleukin-10 (IL-10), a pleiotropic cytokine with an essential role in inflammatory processes, is known to be affected by glycosaminoglycans (GAGs). GAGs are highly negatively charged polysaccharides and integral components of the extracellular matrix with important func...

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Vydáno v:J Biol Chem
Hlavní autoři: Künze, Georg, Köhling, Sebastian, Vogel, Alexander, Rademann, Jörg, Huster, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742770/
https://ncbi.nlm.nih.gov/pubmed/26677224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681759
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