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Identification of the Glycosaminoglycan Binding Site of Interleukin-10 by NMR Spectroscopy

The biological function of interleukin-10 (IL-10), a pleiotropic cytokine with an essential role in inflammatory processes, is known to be affected by glycosaminoglycans (GAGs). GAGs are highly negatively charged polysaccharides and integral components of the extracellular matrix with important func...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Künze, Georg, Köhling, Sebastian, Vogel, Alexander, Rademann, Jörg, Huster, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742770/
https://ncbi.nlm.nih.gov/pubmed/26677224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.681759
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