α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Approximately one-half of the patients who develop clinical atherosclerosis have normal or only modest elevations in plasma lipids, indicating that additional mechanisms contribute to pathogenesis. In view of increasing evidence that inflammation contributes to atherogenesis, we studied the effect o...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Abu-Fanne, Rami, Maraga, Emad, Abd-Elrahman, Ihab, Hankin, Aviel, Blum, Galia, Abdeen, Suhair, Hijazi, Nuha, Cines, Douglas B., Higazi, Abd Al-Roof
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Lipids
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742743/
https://ncbi.nlm.nih.gov/pubmed/26518877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669812
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