α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Approximately one-half of the patients who develop clinical atherosclerosis have normal or only modest elevations in plasma lipids, indicating that additional mechanisms contribute to pathogenesis. In view of increasing evidence that inflammation contributes to atherogenesis, we studied the effect o...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Abu-Fanne, Rami, Maraga, Emad, Abd-Elrahman, Ihab, Hankin, Aviel, Blum, Galia, Abdeen, Suhair, Hijazi, Nuha, Cines, Douglas B., Higazi, Abd Al-Roof
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Lipids
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742743/
https://ncbi.nlm.nih.gov/pubmed/26518877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669812
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