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α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Approximately one-half of the patients who develop clinical atherosclerosis have normal or only modest elevations in plasma lipids, indicating that additional mechanisms contribute to pathogenesis. In view of increasing evidence that inflammation contributes to atherogenesis, we studied the effect o...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Abu-Fanne, Rami, Maraga, Emad, Abd-Elrahman, Ihab, Hankin, Aviel, Blum, Galia, Abdeen, Suhair, Hijazi, Nuha, Cines, Douglas B., Higazi, Abd Al-Roof
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742743/
https://ncbi.nlm.nih.gov/pubmed/26518877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669812
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