α-Defensins Induce a Post-translational Modification of Low Density Lipoprotein (LDL) That Promotes Atherosclerosis at Normal Levels of Plasma Cholesterol

Approximately one-half of the patients who develop clinical atherosclerosis have normal or only modest elevations in plasma lipids, indicating that additional mechanisms contribute to pathogenesis. In view of increasing evidence that inflammation contributes to atherogenesis, we studied the effect o...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Abu-Fanne, Rami, Maraga, Emad, Abd-Elrahman, Ihab, Hankin, Aviel, Blum, Galia, Abdeen, Suhair, Hijazi, Nuha, Cines, Douglas B., Higazi, Abd Al-Roof
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Lipids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742743/
https://ncbi.nlm.nih.gov/pubmed/26518877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669812
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