Neutrophil α-defensins promote thrombosis in vivo by altering fibrin formation, structure, and stability

Inflammation and thrombosis are integrated, mutually reinforcing processes, but the interregulatory mechanisms are incompletely defined. Here, we examined the contribution of α-defensins (α-defs), antimicrobial proteins released from activated human neutrophils, on clot formation in vitro and in viv...

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Abu-Fanne, Rami, Stepanova, Victoria, Litvinov, Rustem I., Abdeen, Suhair, Bdeir, Khalil, Higazi, Mohamed, Maraga, Emad, Nagaswami, Chandrasekaran, Mukhitov, Alexander R., Weisel, John W., Cines, Douglas B., Higazi, Abd Al-Roof
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Thrombosis and Hemostasis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356988/
https://ncbi.nlm.nih.gov/pubmed/30442678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2018-07-861237
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