Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome

In vitro evidence suggests that the bone marrow microenvironment (BMME) is altered in myelodysplastic syndromes (MDSs). Here, we study the BMME in MDS in vivo using a transgenic murine model of MDS with hematopoietic expression of the translocation product NUP98-HOXD13 (NHD13). This model exhibits a...

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Vydáno v:Blood
Hlavní autoři: Balderman, Sophia R., Li, Allison J., Hoffman, Corey M., Frisch, Benjamin J., Goodman, Alexandra N., LaMere, Mark W., Georger, Mary A., Evans, Andrew G., Liesveld, Jane L., Becker, Michael W., Calvi, Laura M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2016
Témata:
Myeloid Neoplasia
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742549/
https://ncbi.nlm.nih.gov/pubmed/26637787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-653113
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