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Biology of the Bone Marrow Microenvironment and Myelodysplastic Syndromes

Myelodysplastic syndromes (MDS) are characterized by cytopenias resulting from ineffective hematopoiesis with a predisposition to transform to acute myeloid leukemia (AML). Recent evidence suggests that the hematopoietic stem cell microenvironment contributes to the pathogenesis of MDS. Inflammation...

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Bibliographic Details
Published in:Mol Genet Metab
Main Authors: Rankin, Erinn B., Narla, Anupama, Park, Joseph K., Lin, Shuo, Sakamoto, Kathleen M.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618471/
https://ncbi.nlm.nih.gov/pubmed/26210353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2015.07.004
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