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Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome
In vitro evidence suggests that the bone marrow microenvironment (BMME) is altered in myelodysplastic syndromes (MDSs). Here, we study the BMME in MDS in vivo using a transgenic murine model of MDS with hematopoietic expression of the translocation product NUP98-HOXD13 (NHD13). This model exhibits a...
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Publicado no: | Blood |
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Principais autores: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742549/ https://ncbi.nlm.nih.gov/pubmed/26637787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-653113 |
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