Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome

In vitro evidence suggests that the bone marrow microenvironment (BMME) is altered in myelodysplastic syndromes (MDSs). Here, we study the BMME in MDS in vivo using a transgenic murine model of MDS with hematopoietic expression of the translocation product NUP98-HOXD13 (NHD13). This model exhibits a...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood
Prif Awduron: Balderman, Sophia R., Li, Allison J., Hoffman, Corey M., Frisch, Benjamin J., Goodman, Alexandra N., LaMere, Mark W., Georger, Mary A., Evans, Andrew G., Liesveld, Jane L., Becker, Michael W., Calvi, Laura M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2016
Pynciau:
Myeloid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742549/
https://ncbi.nlm.nih.gov/pubmed/26637787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-653113
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