Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome

In vitro evidence suggests that the bone marrow microenvironment (BMME) is altered in myelodysplastic syndromes (MDSs). Here, we study the BMME in MDS in vivo using a transgenic murine model of MDS with hematopoietic expression of the translocation product NUP98-HOXD13 (NHD13). This model exhibits a...

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發表在:Blood
Main Authors: Balderman, Sophia R., Li, Allison J., Hoffman, Corey M., Frisch, Benjamin J., Goodman, Alexandra N., LaMere, Mark W., Georger, Mary A., Evans, Andrew G., Liesveld, Jane L., Becker, Michael W., Calvi, Laura M.
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2016
主題:
Myeloid Neoplasia
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742549/
https://ncbi.nlm.nih.gov/pubmed/26637787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-06-653113
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