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Structural basis for collagen recognition by the immune receptor OSCAR

The osteoclast-associated receptor (OSCAR) is a collagen-binding immune receptor with important roles in dendritic cell maturation and activation of inflammatory monocytes as well as in osteoclastogenesis. The crystal structure of the OSCAR ectodomain is presented, both free and in complex with a co...

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Détails bibliographiques
Publié dans:Blood
Auteurs principaux: Zhou, Long, Hinerman, Jennifer M., Blaszczyk, Michal, Miller, Jeanette L. C., Conrady, Deborah G., Barrow, Alexander D., Chirgadze, Dimitri Y., Bihan, Dominique, Farndale, Richard W., Herr, Andrew B.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742545/
https://ncbi.nlm.nih.gov/pubmed/26552697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-667055
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