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OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice
Osteoclasts are terminally differentiated leukocytes that erode the mineralized bone matrix. Osteoclastogenesis requires costimulatory receptor signaling through adaptors containing immunoreceptor tyrosine-based activation motifs (ITAMs), such as Fc receptor common γ (FcRγ) and DNAX-activating prote...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Clinical Investigation
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3163954/ https://ncbi.nlm.nih.gov/pubmed/21841309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45913 |
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