OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

Osteoclasts are terminally differentiated leukocytes that erode the mineralized bone matrix. Osteoclastogenesis requires costimulatory receptor signaling through adaptors containing immunoreceptor tyrosine-based activation motifs (ITAMs), such as Fc receptor common γ (FcRγ) and DNAX-activating prote...

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Detalhes bibliográficos
Main Authors: Barrow, Alexander David, Raynal, Nicolas, Andersen, Thomas Levin, Slatter, David A., Bihan, Dominique, Pugh, Nicholas, Cella, Marina, Kim, Taesoo, Rho, Jaerang, Negishi-Koga, Takako, Delaisse, Jean-Marie, Takayanagi, Hiroshi, Lorenzo, Joseph, Colonna, Marco, Farndale, Richard W., Choi, Yongwon, Trowsdale, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3163954/
https://ncbi.nlm.nih.gov/pubmed/21841309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI45913
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