Structural basis for collagen recognition by the immune receptor OSCAR

The osteoclast-associated receptor (OSCAR) is a collagen-binding immune receptor with important roles in dendritic cell maturation and activation of inflammatory monocytes as well as in osteoclastogenesis. The crystal structure of the OSCAR ectodomain is presented, both free and in complex with a co...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Zhou, Long, Hinerman, Jennifer M., Blaszczyk, Michal, Miller, Jeanette L. C., Conrady, Deborah G., Barrow, Alexander D., Chirgadze, Dimitri Y., Bihan, Dominique, Farndale, Richard W., Herr, Andrew B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Plenary Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742545/
https://ncbi.nlm.nih.gov/pubmed/26552697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-08-667055
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