Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease

Mutations or inactivation of parkin, an E3 ubiquitin ligase, are associated with familial form or sporadic Parkinson’s disease (PD), respectively, which manifested with the selective vulnerability of neuronal cells in substantia nigra (SN) and striatum (STR) regions. However, the underlying molecula...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Song, Pingping, Li, Shanshan, Wu, Hao, Gao, Ruize, Rao, Guanhua, Wang, Dongmei, Chen, Ziheng, Ma, Biao, Wang, Hongxia, Sui, Nan, Deng, Haiteng, Zhang, Zhuohua, Tang, Tieshan, Tan, Zheng, Han, Zehan, Lu, Tieyuan, Zhu, Yushan, Chen, Quan
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742389/
https://ncbi.nlm.nih.gov/pubmed/26746706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0230-9
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