Parkin promotes proteasomal degradation of p62: implication of selective vulnerability of neuronal cells in the pathogenesis of Parkinson’s disease

Mutations or inactivation of parkin, an E3 ubiquitin ligase, are associated with familial form or sporadic Parkinson’s disease (PD), respectively, which manifested with the selective vulnerability of neuronal cells in substantia nigra (SN) and striatum (STR) regions. However, the underlying molecula...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Protein Cell
Egile Nagusiak: Song, Pingping, Li, Shanshan, Wu, Hao, Gao, Ruize, Rao, Guanhua, Wang, Dongmei, Chen, Ziheng, Ma, Biao, Wang, Hongxia, Sui, Nan, Deng, Haiteng, Zhang, Zhuohua, Tang, Tieshan, Tan, Zheng, Han, Zehan, Lu, Tieyuan, Zhu, Yushan, Chen, Quan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Higher Education Press 2016
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742389/
https://ncbi.nlm.nih.gov/pubmed/26746706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-015-0230-9
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