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Questions and answers about myostatin, GDF11, and the aging heart
Myostatin and GDF11 are highly homologous TGFβ family members implicated in skeletal and cardiac muscle growth. Myostatin promotes muscle wasting. In contrast, GDF11 was identified as a factor that reverses aging-related cardiac hypertrophy, and in separate experiments, GDF11 supplementation was lin...
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| Publicat a: | Circ Res |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4742361/ https://ncbi.nlm.nih.gov/pubmed/26837737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307861 |
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