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Questions and answers about myostatin, GDF11, and the aging heart

Myostatin and GDF11 are highly homologous TGFβ family members implicated in skeletal and cardiac muscle growth. Myostatin promotes muscle wasting. In contrast, GDF11 was identified as a factor that reverses aging-related cardiac hypertrophy, and in separate experiments, GDF11 supplementation was lin...

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Detalhes bibliográficos
Publicado no:Circ Res
Autor principal: McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742361/
https://ncbi.nlm.nih.gov/pubmed/26837737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307861
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