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Questions and answers about myostatin, GDF11, and the aging heart

Myostatin and GDF11 are highly homologous TGFβ family members implicated in skeletal and cardiac muscle growth. Myostatin promotes muscle wasting. In contrast, GDF11 was identified as a factor that reverses aging-related cardiac hypertrophy, and in separate experiments, GDF11 supplementation was lin...

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Bibliografske podrobnosti
izdano v:Circ Res
Glavni avtor: McNally, Elizabeth M.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742361/
https://ncbi.nlm.nih.gov/pubmed/26837737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.307861
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