Biochemistry and Biology of GDF11 and Myostatin: similarities, differences and questions for future investigation

Growth differentiation factor 11 (GDF11) and myostatin (MSTN or GDF8) are closely related members of the transforming growth factor β superfamily (TGFβ) and are often perceived to serve similar or overlapping roles. Yet, despite commonalities in protein sequence, receptor utilization and signaling,...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Walker, Ryan G., Poggioli, Tommaso, Katsimpardi, Lida, Buchanan, Sean M., Oh, Juhyun, Wattrus, Sam, Heidecker, Bettina, Fong, Yick W., Rubin, Lee L., Ganz, Peter, Thompson, Thomas B., Wagers, Amy J., Lee, Richard T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818972/
https://ncbi.nlm.nih.gov/pubmed/27034275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.116.308391
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