Natural killer cells facilitate PRAME-specific T-cell reactivity against neuroblastoma

Neuroblastoma is the most common solid tumor in children with an estimated 5-year progression free survival of 20–40% in stage 4 disease. Neuroblastoma actively avoids recognition by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). Although immunotherapy has gained traction for neurobla...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Spel, Lotte, Boelens, Jaap-Jan, van der Steen, Dirk M., Blokland, Nina J.G., van Noesel, Max M., Molenaar, Jan J., Heemskerk, Mirjam H.M., Boes, Marianne, Nierkens, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742140/
https://ncbi.nlm.nih.gov/pubmed/26452036
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