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Antitumor immune responses mediated by dendritic cells: How signals derived from dying cancer cells drive antigen cross-presentation

Dendritic cells (DCs) are essential for the induction of adaptive immune responses against malignant cells by virtue of their capacity to effectively cross-present exogenous antigens to T lymphocytes. Dying cancer cells are indeed a rich source of antigens that may be harnessed for the development o...

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Detalhes bibliográficos
Main Authors: Spel, Lotte, Boelens, Jaap-Jan, Nierkens, Stefan, Boes, Marianne
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3894247/
https://ncbi.nlm.nih.gov/pubmed/24482744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.26403
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