Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines

Autophagy is an evolutionarily conserved survival pathway in eukaryote and is frequently upregulated in cancer cells after chemotherapy or targeted therapy. Thus induction of autophagy has emerged as a drug resistance mechanism. In this study, we found that crizotinib induced a high level of autopha...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: You, Liangkun, Shou, Jiawei, Deng, Danchen, Jiang, Liming, Jing, Zhao, Yao, Junlin, Li, Hongsen, Xie, Jiansheng, Wang, Zhanggui, Pan, Qin, Pan, Hongming, Huang, Wendong, Han, Weidong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741894/
https://ncbi.nlm.nih.gov/pubmed/26384345
Tagiau: Ychwanegu Tag
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