Crizotinib induces autophagy through inhibition of the STAT3 pathway in multiple lung cancer cell lines

Autophagy is an evolutionarily conserved survival pathway in eukaryote and is frequently upregulated in cancer cells after chemotherapy or targeted therapy. Thus induction of autophagy has emerged as a drug resistance mechanism. In this study, we found that crizotinib induced a high level of autopha...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: You, Liangkun, Shou, Jiawei, Deng, Danchen, Jiang, Liming, Jing, Zhao, Yao, Junlin, Li, Hongsen, Xie, Jiansheng, Wang, Zhanggui, Pan, Qin, Pan, Hongming, Huang, Wendong, Han, Weidong
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741894/
https://ncbi.nlm.nih.gov/pubmed/26384345
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