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Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib
Autophagy is a critical survival pathway for cancer cells under conditions of stress. Thus, induction of autophagy has emerged as a drug resistance mechanism. This study is to determine whether autophagy is activated by a novel multikinase inhibitor linifanib, thereby impairing the sensitivity of he...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4202209/ https://ncbi.nlm.nih.gov/pubmed/25327881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06683 |
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