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Autophagy inhibition sensitizes hepatocellular carcinoma to the multikinase inhibitor linifanib

Autophagy is a critical survival pathway for cancer cells under conditions of stress. Thus, induction of autophagy has emerged as a drug resistance mechanism. This study is to determine whether autophagy is activated by a novel multikinase inhibitor linifanib, thereby impairing the sensitivity of he...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pan, Hongming, Wang, Zhanggui, Jiang, Liming, Sui, Xinbing, You, Liangkun, Shou, Jiawei, Jing, Zhao, Xie, Jiansheng, Ge, Weiting, Cai, Xiujun, Huang, Wendong, Han, Weidong
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4202209/
https://ncbi.nlm.nih.gov/pubmed/25327881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06683
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