Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

BACKGROUND: Companion diagnostics aim to identify patients that will respond to targeted therapies, therefore increasing the clinical efficacy of such drugs. Less is known about their influence on safety and tolerability of targeted anti-cancer agents. METHODS AND FINDINGS: Randomized trials evaluat...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ocana, Alberto, Ethier, Josee-Lyne, Díez-González, Laura, Corrales-Sánchez, Verónica, Srikanthan, Amirrtha, Gascón-Escribano, María J., Templeton, Arnoud J., Vera-Badillo, Francisco, Seruga, Bostjan, Niraula, Saroj, Pandiella, Atanasio, Amir, Eitan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741844/
https://ncbi.nlm.nih.gov/pubmed/26446908
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