Influence of companion diagnostics on efficacy and safety of targeted anti-cancer drugs: systematic review and meta-analyses

BACKGROUND: Companion diagnostics aim to identify patients that will respond to targeted therapies, therefore increasing the clinical efficacy of such drugs. Less is known about their influence on safety and tolerability of targeted anti-cancer agents. METHODS AND FINDINGS: Randomized trials evaluat...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Ocana, Alberto, Ethier, Josee-Lyne, Díez-González, Laura, Corrales-Sánchez, Verónica, Srikanthan, Amirrtha, Gascón-Escribano, María J., Templeton, Arnoud J., Vera-Badillo, Francisco, Seruga, Bostjan, Niraula, Saroj, Pandiella, Atanasio, Amir, Eitan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741844/
https://ncbi.nlm.nih.gov/pubmed/26446908
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