Activation of the PI3K/mTOR/AKT Pathway and Survival in Solid Tumors: Systematic Review and Meta-Analysis

BACKGROUND: Aberrations in the phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR)/AKT pathway are common in solid tumors. Numerous drugs have been developed to target different components of this pathway. However the prognostic value of these aberrations is unclear. METHODS: P...

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Main Authors: Ocana, Alberto, Vera-Badillo, Francisco, Al-Mubarak, Mustafa, Templeton, Arnoud J., Corrales-Sanchez, Verónica, Diez-Gonzalez, Laura, Cuenca-Lopez, María D., Seruga, Bostjan, Pandiella, Atanasio, Amir, Eitan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002433/
https://ncbi.nlm.nih.gov/pubmed/24777052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095219
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