Cardiovascular Toxicity of Multi-Tyrosine Kinase Inhibitors in Advanced Solid Tumors: A Population-Based Observational Study

BACKGROUND: Treatment with small molecule tyrosine kinase inhibitors (TKIs) has improved survival in many cancers, yet has been associated with an increased risk of adverse events. Warnings of cardiovascular events are common in drug labels of many TKIs. Despite these warnings, cardiovascular toxici...

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Publicado en:PLoS One
Autores principales: Srikanthan, Amirrtha, Ethier, Josee-Lyne, Ocana, Alberto, Seruga, Bostjan, Krzyzanowska, Monika K., Amir, Eitan
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376902/
https://ncbi.nlm.nih.gov/pubmed/25815472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122735
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