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Efficacy, safety and tolerability of drugs studied in phase 3 randomized controlled trials in solid tumors over the last decade

Data suggest that for newly approved cancer drugs safety and tolerability are worse than in control arms of registration trials. Less is known about the balance between efficacy and toxicity of drugs studied in unselected phase 3 randomized controlled trials (RCTs) including those not resulting in r...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Ribnikar, Domen, Goldvaser, Hadar, Veitch, Zachary W., Ocana, Alberto, Templeton, Arnoud J., Šeruga, Boštjan, Amir, Eitan
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8149406/
https://ncbi.nlm.nih.gov/pubmed/34035370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-90403-3
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