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Cardiovascular Toxicity of Multi-Tyrosine Kinase Inhibitors in Advanced Solid Tumors: A Population-Based Observational Study

BACKGROUND: Treatment with small molecule tyrosine kinase inhibitors (TKIs) has improved survival in many cancers, yet has been associated with an increased risk of adverse events. Warnings of cardiovascular events are common in drug labels of many TKIs. Despite these warnings, cardiovascular toxici...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Srikanthan, Amirrtha, Ethier, Josee-Lyne, Ocana, Alberto, Seruga, Bostjan, Krzyzanowska, Monika K., Amir, Eitan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376902/
https://ncbi.nlm.nih.gov/pubmed/25815472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122735
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