BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells

Uveal melanoma (UM) is an aggressive intraocular malignancy with limited therapeutic options. Both primary and metastatic UM are characterized by oncogenic mutations in the G-protein alpha subunit q and 11. Furthermore, nearly 40% of UM has amplification of the chromosomal arm 8q and monosomy of chr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Ambrosini, Grazia, Sawle, Ashley D., Musi, Elgilda, Schwartz, Gary K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741774/
https://ncbi.nlm.nih.gov/pubmed/26397223
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker